Fig. 2.

(A) Exposure to house dust alters cecal microbiome composition. UniFrac-based cluster analysis of cecal microbiota of control, D dust- and NP dust-supplemented animals reveals distinct microbiota compositions in each treatment group. (B) Phylogenetic tree displaying all taxa that exhibited significant (P < 0.05; q < 0.15) relative enrichment (red bars) or depletion (green bars) in airway-protected mice supplemented with D-associated house dust compared with unprotected control animals. Phyla are indicted by color: Acidobacteria (light blue), Actinobacteria (teal), Bacteriodetes (purple), Firmicutes (green), Proteobacteria (red), and other (orange). Family designation of highly enriched or depleted taxa are indicated.