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(A) The effect of treatment with the GHRH agonist JI-34 (50 µg/kg/d or 1 µg/mouse/d) (J) and doxorubicin (DOX; D) (13 µmol/kg/wk) alone and in combination on the growth of U-87 MG, human GBM tumors xenotransplanted to nude mice. Numbers at labels represent the number of successfully implanted tumors. (B) Final weights of necropsied tumor samples compared with the control. (C) Numbers at the end of each curve show the tumor doubling times. *P < 0.05 vs. control.
