Table 5.

Multivariate analysis results for OS/NRM using all data as time-dependent covariates

		OS				NRM
Parameter	Category	p-value	HR	95% HR CI		p-value	HR	95% HR CI
NIH GI 0-3	Involved	0.02	1.69	1.10	2.60	0.02	1.89	1.13	3.15
	Not involved		1.00				1.00
Bilirubin	Involved	<0.001	3.73	2.16	6.46	<0.001	4.44	2.32	8.52
	Not involved		1.00				1.00
Site	FHCRC	0.13	0.72	0.47	1.10	0.27	0.74	0.44	1.26
	Other sites		1.00				1.00
Case type	Incident	0.77	0.93	0.56	1.53	0.83	0.94	0.51	1.73
	Prevalent		1.00				1.00
Time from HCT to enrollment	< 12 months	0.17	1.43	0.86	2.36	0.90	0.96	0.52	1.80
	≥ 12 months		1.00				1.00
Platelet	< 100K	<0.001	2.70	1.64	4.44	<0.001	3.57	1.98	6.45
	≥ 100K		1.00				1.00
KPS	< 80	<0.001	3.10	1.93	4.98	<0.001	3.43	1.87	6.29
	Missing	0.07	1.67	0.97	2.89	0.03	2.11	1.06	4.18
	≥ 80		1.00				1.00
Age at transplant, years	≥ 50	0.90	1.03	0.67	1.57	0.68	0.90	0.53	1.51
	< 50		1.00				1.00
Donor match	Matched unrelated	0.59	1.14	0.72	1.81	0.29	1.37	0.77	2.45
	Mismatched	0.27	1.36	0.79	2.35	0.33	1.39	0.71	2.72
	Matched related		1.00				1.00
Donor gender combination	Female donor male patients	0.72	0.92	0.59	1.43	0.43	0.80	0.46	1.39
	Others		1.00				1.00
Conditioning type	Myeloablative	0.34	0.82	0.54	1.24	0.09	0.64	0.39	1.07
	Non-myeloablative		1.00				1.00
Prior acute GVHD	Yes	0.47	0.85	0.56	1.31	0.65	0.89	0.52	1.51
	No		1.00				1.00