Table 2.

Maximum severity^a (Grade 3+) AEs, Per patient (N=35)

Adverse event	Grade 3	Grade 4
Thrombocytopenia	4 (11%)	0
Anemia	2 (6%)	0
Diarrhea	2 (6%)	0
Fatigue	2 (6%)	0
Rash/Desquamation	1 (3%)	0
Thrombosis	0	2 (6%)
Hepatic failure	0	1 (3%)
SGOT (AST)	3 (9%)	0
SGPT (ALT)	2 (6%)	0
Hyponatremia	2 (6%)	0
Ileus	1 (3%)	0
Hyperglycemia	1 (3%)	0
Hypoglycemia	0	1 (3%)
Hypotension	1 (3%)	0
Muscle weakness	1 (3%)	0
Dizziness	1 (3%)	0
Cognitive disorder	1 (3%)	0

^aNCI CTCAE V3.0. Reported are AEs deemed at least possibly related to BORTEZOMIB