Figure 6.

Programmed electrical stimulation in SK3^T/T, SK3^+/T, and WT mice. (A) Percentage of 1-month-old WT, SK3^+/T, and SK3^T/T mice with inducible AF/atrial arrhythmias on programmed electrical stimulation. (B) Representative example of induction of AF after rapid atrial pacing (cycle length 30 ms) in an SK3^T/T mouse. The top tracing is an intracardiac electrogram from the atrioventricular junction (A) demonstrating atrial and ventricular activity. The lower tracing is an intracardiac electrogram from the right ventricular apex (V) demonstrating ventricular activity. The intracardiac electrograms demonstrate rapid atrial activity with variable conduction to the ventricle.