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. 2014 Jan 8;10:34–114. doi: 10.3762/bjoc.10.6

Table 16.

Synthesis of 1,2-dioxanes by the Isayama–Mukaiyama method.

1,5-Diene 213 Reaction conditionsa 1,2-Dioxane 214 Yield, % Reference
graphic file with name Beilstein_J_Org_Chem-10-34-i243.jpg 1) Co(modp)2, O2, Et3SiH, ClCH2CH2Cl,
2–6 h
2) HCl/MeOH		 graphic file with name Beilstein_J_Org_Chem-10-34-i244.jpg 13–64 [249]
graphic file with name Beilstein_J_Org_Chem-10-34-i245.jpg 1) Co(modp)2, O2, Et3SiH, ClCH2CH2Cl,
1 h
2) HCl/MeOH		 graphic file with name Beilstein_J_Org_Chem-10-34-i246.jpg 22 [318–319]

amodp = 1-morpholino-5,5-dimethyl-1,2,4-hexanetrionate.