Table 23.

Examples of 1,2,4-trioxanes 357 synthesized based on epoxides 355.

Epoxide 355	Carbonyl compound	Reaction conditions	1,2,4-Trioxane 357	Yield i) 356 ii) 357, %	Ref.
		1) MoO2(acac)2, H2O2 , Et2O, MgSO4 2) TsOH, CH2Cl2, rt		i) 59 ii) 95	[405]
				i) 59 ii) 69	[405]
		1) MoO2(acac)2, H2O2, THF, MgSO4 2) 10-camphor- sulfonic acid, CH2Cl2, rt		i) 29 ii) 46	[405]
		1) H2O2, Et2O, 0 °C, 4 h 2) H2SO4, CH2Cl2, rt, 4 d		i) 8 ii) 28	[406]
		1) MoO2(acac)2, H2O2, Et2O, MgSO4, rt, 22 h 2) TsOH, CH2Cl2, rt, 5 h		i) 98 ii) 92	[407]
		1) MoO2(acac)2, H2O2, Et2O 2) 10-camphor- sulfonic acid, CH2Cl2		i) 25 ii) 39	[407]
		1) MoO2(acac)2, H2O2 , Et2O, MgSO4 2) BF3·Et2O, CH2Cl2, −78 °C to 0 °C, 5 h		i) - ii) 27–35	[175] [176]