Table 1. Summary of results from studies reporting prevalence of oral HPV DNA among HIV-infected adults, contrasted with US general population results.
| Study | Description | Sample Size | Sample Method | Any HPV* | Oncogenic HPV& | HPV16 | Multiple types |
|---|---|---|---|---|---|---|---|
| Coutlee STD 1997[19] | US men and women | 201 | oral brush | 14% | 12% | 3.0% | 0.5% |
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| Kreimer et al JID 2004[3] | US men and women | 190 | oral rinse/brush biopsy | 25% | 14% | --- | 5.8% |
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| Cameron STD 2005[17] | US men and women | 98 | Saliva | 37% | 26% | 6.1% | 7.0% |
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| Marais JMV 2008[23] | South African women | 33 | oral brush | 33% | 12% | 3.0% | 9.1% |
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| Richter JOPM 2008[24] | South African women | 30 | oral brush | 20% | 7% | 0.0% | 6.7% |
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| Fakhry Plos One 2010∼[25] | US men and women | 112 | oral rinse | 45% | 26% | 5.9% | --- |
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| Parisi BMCID 2011[26] | Italian MSM | 166 | oral swab | 20% | 1.5% | 0.8% | --- |
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| Beachler et al CEBP 2012[16**] | US MSM and women | 379 | oral rinse | 40% | 21% | 6.1% | 19% |
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| Read et al Plos One 2012[20*] | Australian MSM | 249 | oral rinse/brush | 19% | 8% | 4.4% | 7.2% |
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| Del Mistro STD 2012[27*] | Italian men and women | 100 | Saliva | 37% | 13% | 3.0% | 6.0% |
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| Steinau et al JOPM 2012[28**] | US men and women | 100 | oral rinse | 39% | 24% | 3.0% | 17% |
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| Fatahzadeh et al OOOOE 2013 [29*] | US men and women | 52 | oral rinse | 38% | 23% | 6.0% | --- |
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| Videla et al STD 2013[21**] | Spanish men | 650 | oral brush/rinse | 16% | 15% | 5.2% | 3.8% |
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| Beachler et al JID 2013[30*] | US men and women | 404 | oral rinse | 28% | 13% | 2.3% | 11% |
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| ------ | HIV+ Summaryˆ | 2764 | ----- | 26%ˆ | 15%ˆ | 4.2%ˆ | 8.5%ˆ |
| Gillison et al JAMA 2012[22*] | US General Population+ | 5501 | oral rinse | 7% | 3.7% | 1.0% | --- |
Number of total alpha HPV types tested varied from 9 (Coutlee 1997) to 47 (Parisi 2011) although untyped genotypes were included in the prevalence estimates for several studies (Coutlee 1997, Cameron 2005, Del Mistro 2012). Cutaneous HPV types were not included in this summary.
Number of oncogenic types varied from 7 (Coutlee 1997) to 22 (Kreimer 2004, Marais 2008) while most considered 13-14 types to be oncogenic
Average point prevalences reported
Pooled oral HPV prevalence summary includes studies with differences in sample collection, processing, number of HPV types tested, DNA detection methods, and the study participant characteristics
Data from a representative sample of the US population, from the National Health and Nutrition Examination Survey (NHANES)