Fig. 2.
Left panel: Dose-related hyperglycemic effect of the stable TRH analog RX77368 microinjected into the RVLM of overnight-fasted Wistar rats. Each point represents the mean ± SEM of the number of rats indicated in the parenthesis. * P < 0.05 compared with the effect of microinjection into sites outside of the RVLM. # P< 0.05 compared with the basal levels of the same group. Right panel: Effective and ineffective microinjection sites of the TRH analog RX77368 to induce hyperglycemia, marked on plates reproduced from the atlas of Paxinos & Watson (Paxinos et al., 1997).