Figure 5. Integration sites of non-induced proviruses.

(A) Distribution of integration sites of non-induced proviruses. Intron and exon boundaries are determined as previously described (Shan et al., 2011).

(B) Transcription level of host genes in which non-induced proviruses were integrated. Transcription levels were determined by SAGE analysis of Bcl-2 transduced activated and resting primary CD4⁺ T cells as previously described (Shan et al., 2011). Blue circles, transcript levels in resting and activated CD4⁺ T cells. Red squares, transcript levels for the subset of genes in which integration sites of non-induced proviruses were mapped.

(C) Transcriptional orientation of non-induced proviruses relative to the host gene.