Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jan 20;9(1):e84072. doi: 10.1371/journal.pone.0084072

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Hagiwara et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Broad range of differentiation potential in spheres derived from craniofacial EGFP⁺ cells. All groups of spheres differentiated into neurons, glial cells, myofibroblasts and adipocytes. Chondrocytes were differentiated from only spheres derived from craniofacial EGFP⁺ cells and trunk EGFP⁻ cells. Osteocytes were differentiated from all groups of spheres except for spheres derived from trunk EGFP⁺ cells. (B–F) Spheres derived from trunk EGFP⁺ cells showed peripheral neuronal lineages. Quantitative analyses of the potential for differentiation into neurons (B), oligodendrocytes (C), glial cells including Schwann cells (D), and myofibroblasts (E) by counting the number of cells positive for specific markers. (F) Quantification of adipocyte differentiation by relative fluorescence units (RFU). Excitation and emission of Adipo Red-stained cells was measured at 485 and 535 nm, respectively. Trunk EGFP⁻ cells showed the highest differentiation potential among the four groups.