Table 2. Effect of high pressure on excluded volume (V _ex), solvent accessible surface area (SASA) and isothermal compressibility (κ_T).

	V ex			SASA			κT
Label	0.1 MPa	60 MPa	Δ	0.1 MPa	60 MPa	Δ	0.1 MPa	60 MPa	Δ
Rab	7.39±0.02	7.37±0.02	−0.02	1.82±0.02	1.84±0.02	0.02	0.14±0.02	0.13±0.02	−0.01
Ac1W	7.40±0.02	7.41±0.03	0.01	1.84±0.02	1.87±0.02	0.03	0.14±0.02	0.15±0.04	0.01
Ac1Q	7.40±0.02	7.39±0.02	−0.01	1.84±0.02	1.86±0.03	0.02	0.14±0.02	0.14±0.01	−0.01
Ac2	7.41±0.03	7.36±0.02	−0.05	1.84±0.02	1.83±0.02	−0.01	0.15±0.04	0.14±0.02	−0.01
Arm	7.39±0.02	7.36±0.03	−0.03	1.83±0.02	1.84±0.02	0.01	0.13±0.02	0.15±0.04	0.02
Yaq	7.42±0.02	7.40±0.02	−0.02	1.85±0.02	1.87±0.02	0.02	0.13±0.02	0.15±0.03	0.02

Units: V _ex (10⁴ ų), SASA (10⁴ Ų), κ_T, (GPa⁻¹). Δ = X _{60 MPa} – X _{0.1 MPa} where X = V _ex, SASA, or κ_T. The value after “±” indicates standard deviation.