Table 3. Proximal CME context in midline and tracheal enhancers.
Mostcommon1 | Number2 | Neverfound3 | Tissue4 | PredictedConsensus5 |
A ACGTG C | 14 | A ACGTG G | midline | (A/G/T) ACGTG C |
T ACGTG A | 10 | G ACGTG T | trachea | (A/T) ACGTG (A/C/T) |
T ACGTG C | 10 | T ACGTG G | both | (A/T) ACGTG C |
Sixty-six CMEs were found in all midline and tracheal enhancers examined. 1The nucleotides found directly 5′ and 3′ of the CME within the enhancers and 2 the number of times that sequence was found in all the midline and tracheal enhancers are listed. The three sequence contexts found in the left column represent 52% of the CMEs found within all enhancers (34/66; Table S4), while 3other sequence contexts were not found in any enhancers. 4, 5Sequences flanking the sixty-six CMEs were used to derive a consensus sequence for genes expressed in the midline, trachea or both tissues.