Table 4. Haplotype of 4 SNPs rs4586354, rs3783903, rs2236131 and rs1740689 in ITPK1 gene and their relative risks for NTDs.
Haplotype | rs4586354 | rs3783903 | rs2236131 | rs1740689 | Frequency | OR(95%CI) | P |
Wild-Haplotype | T | A | G | A | 0.5454 | 1 | |
Mut-Haplotype | C | G | A | G | 0.1898 | 1.64(1.15,233) | 0.0063 |
Abbreviations: NTD, neural tube defect; OR, odds ratio; 95% CI, 95% confidence interval.