Table 1. Baseline characteristics of acute ischemic stroke patients and normal cases.
| Characteristics | All(n = 240) | Normal cases (n = 100) | pa |
| Male sex (%) | 166(69.2) | 70(70.0) | NS |
| Age (years), median(IQR) | 67(53–76) | 66(52–77) | NS |
| Stroke severity, median NIHSS score (IQR) | 8(5–11) | – | – |
| Infarct volume(mL, IQR; n = 183) | 10(7–22) | – | – |
| Vascular risk factors no. (%) | |||
| Diabetes mellitus | 54(22.5) | – | – |
| Hypertension | 172(71.7) | ||
| Coronary heart disease | 61(25.4) | – | – |
| Atrial fibrillation | 55(22.9) | ||
| Hypercholesterolemia | 66(27.5) | – | – |
| Family history for stroke | 52(21.7) | – | – |
| Smoking habit | 49(20.4) | – | – |
| Clinical findings median(IQR) | |||
| Temperature (°C) | 37.0(36.4–37.4) | 36.5(36.3–36.8) | <0.01 |
| BMI (kg m−2) | 24.8(23.2–27.4) | 24.7(23.3–27.2) | NS |
| Heart rate (beats min−1) | 82(72–91) | 79(67–87) | NS |
| Systolic blood pressure(mmHg) | 158(144–175) | 127(112–134) | <0.001 |
| Diastolic blood pressure(mmHg) | 94(80–99) | 80(75–86) | <0.01 |
| Laboratory findings (median, IQR) | |||
| Glucose(mmol L−1) | 5.99(5.52–6.68) | 5.45(4.76–5.93) | <0.001 |
| C-reactive protein (mgL−1) | 5.5(3.3–9.3) | 3.2(2.5–6.6) | <0.01 |
| Leucocyte count (×103 m L−1) | 8.2(6.3–9.4) | 8.1(6.2–9.3) | NS |
| PT(second) | 12.3(11.2–1.3.1) | 11.1(10.6–11.6) | <0.01 |
| APTT(second) | 28.3(25.9–30.2) | 26.9(24.5–28.6) | <0.01 |
| TT(second) | 18.3(17.7–19.1) | 18.1(17.6–18.9) | NS |
| FBG(g L−1) | 3.54(3.05–3.99) | 2.93(2.34–3.66) | <0.01 |
| D-dimer(mg L−1) | 0.88(0.28–2.11) | 0.31(0.17–0.74) | <0.001 |
| Stroke syndrome no. (%) | |||
| TACS | 31(12.9) | – | – |
| PACS | 95(39.6) | – | – |
| LACS | 55(22.9) | ||
| POCS | 59(24.6) | – | – |
| Stroke etiology no. (%) | |||
| Small-vessel occlusive | 47(19.6) | – | – |
| Large-vessel occlusive | 49(20.4) | ||
| Cardioembolic | 98(40.8) | – | – |
| Other | 22(9.2) | – | – |
| Unknown | 24(10.0) | – | – |
IQR, interquartile range; TACS, total anterior circulation syndrome; LACS, lacunar syndrome; PACS, partial anterior circulation syndrome; POCS, posterior circulation syndrome; NIHSS, National Institutes of Health Stroke Scale; CRP, C-reactive protein; PT, prothrombin time; APTT, activated partial thromboplastin time; TT, thrombin time; FBG, fibrinogen.
a p value was assessed using Mann-Whitney U test or χ2 test.