Figure 3.

Schematic of collagen organization. A) Tropocollagen organization of triple helical polypeptides that consists of a repeating Gly-X-Y (where X is often proline and Y is often hydroxyproline) amino acid sequence to form a right handed coiled-coil ; B) Collagen helices self-assemble into collagen fibrils via aldol-histidine and aldol crosslinking; C: Collagen fibrils further organize into via end-to-end self-assembly into collagen fibers.