Figure 1. Aged α_1AKO mice. Comparison of mean mouse weight (A), isolated prostate weight (B) and mean contractile response to 80 mM KCl Krebs-Henseleit solution (C) from aged wild-type (WT, open columns) and α_1A-adrenoceptor knockout mice (α_1AKO, black columns). Columns represent mean weight/contractile force ± S.E.M., n = 10–14. p-values, **p < 0.01 vs. control, were calculated by an unpaired t-test and represent the probability of genotype affecting prostate weight in the aged mouse.