Table 1. Simulations performed in this study.

	Name	Simulation details†	Temperature (K)	No of Trajectories#	Simulation time (ns)*
1	DEGLYCO	Fc deglycosylated	300	2	100
2	M3N2	Fc with truncated glycans‡	300	2	100
3	G2F	Fc with intact glycans but no sialyic acids	300	2	100
4	DEGLYCO	Fc deglycosylated	375	2	100
5	M3N2	Fc with truncated glycans‡	375	2	100
6	G2F	Fc with intact glycans but no sialyic acid	375	2	100

^† See Figure 2 for information on glycan carbohydrates. ^‡Missing GAL7/10 and NAG6/9. ^# Total number of simulations was 12. *Total simulation time in this study was 1.2 μs.