Figure 5. Recruitment of myeloid effector cells by differently glycosylated IgA2 antibodies. The capacity of differently glycosylated wild type and d471-mutated IgA2 antibodies to mediate ADCC of human A431 tumor cells was analyzed in⁵¹chromium release assays using isolated granulocytes or monocytes as effector cells. Results are shown as “mean ± SEM” of “specific lysis [%]” of at least three independent experiments.