Table 3.
Relationship between maternal self-reported hours of nightly sleep duration and plasma leptin concentrations in early pregnancy: estimates linear regression coefficients for the participants of the Omega Study, Seattle and Tacoma, Washington, 1996-2000
|
Hours of sleep during pregnancy |
N |
MODEL 1 |
MODEL 2 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| β | SE (β) | 95% CI | P-value | β | SE (β) | 95% CI | P-value | ||
|
All women |
|
|
|
|
|
|
|
|
|
| ≤5 |
28 |
4.38 |
3.76 |
(−2.99, 11.76) |
0.24 |
4.77 |
2.88 |
(−0.89, 10.43) |
0.10 |
| 6 |
44 |
−0.05 |
2.56 |
(−5.08, 4.98) |
0.99 |
1.85 |
2.07 |
(−2.21, 5.91) |
0.37 |
| 7-8 |
485 |
Reference |
|
|
|
Reference |
|
|
|
| ≥9 |
273 |
2.60 |
1.30 |
(0.04, 5.16) |
0.05 |
1.77 |
1.05 |
(−0.30, 3.83) |
0.09 |
| Adjusted R2 |
|
0.02 |
|
|
|
0.34 |
|
|
|
|
Lean women |
|
|
|
|
|
|
|
|
|
| ≤5 |
23 |
1.24 |
2.85 |
(−4.35,6.83) |
0.66 |
1.81 |
2.84 |
(−3.76, 7.38) |
0.52 |
| 6 |
34 |
−0.58 |
2.36 |
(−5.23, 4.06) |
0.81 |
1.47 |
2.26 |
(−2.96, 5.91) |
0.51 |
| 7-8 |
379 |
Reference |
|
|
|
Reference |
|
|
|
| ≥9 |
205 |
1.10 |
1.18 |
(−1.22, 3.42) |
0.35 |
0.86 |
1.09 |
(−1.28, 3.00) |
0.43 |
| Adjusted R2 |
|
0.02 |
|
|
|
0.15 |
|
|
|
|
Overweight/obese women |
|
|
|
|
|
|
|
|
|
| ≤5 |
5 |
24.99 |
4.06 |
(16.97, 33.01) |
<0.001 |
21.96 |
5.30 |
(11.50, 32.43) |
<0.001 |
| 6 |
10 |
1.40 |
5.47 |
(−9.39, 12.20) |
0.80 |
3.95 |
4.86 |
(−5.63, 13.53) |
0.42 |
| 7-8 |
106 |
Reference |
|
|
|
Reference |
|
|
|
| ≥9 |
68 |
4.61 |
2.88 |
(−1.07, 10.30) |
0.11 |
4.29 |
2.62 |
(−0.87, 9.46) |
0.09 |
| Adjusted R2 | 0.07 | 0.25 | |||||||
Separate models were fit for all, lean (BMI <25 kg/m2), and overweight BMI ≥25 kg/m2) women, respectively.
Model 1: reported coefficients adjusted for maternal age, race/ethnicity, and marital status; and Model 2: Model 1 + maternal pre-pregnancy body mass index.
β, Estimated coefficient; SE (β), Standard error of the estimated coefficient; 95% CI, 95% confidence interval.