Table 1.

OMR genes implicated in schizophrenia.

Gene	Genetic evidence	PGC-SWE P	Rank	Altered gene expression	Altered proteome
ANK3	Athanasiu et al. (2010), Roussos et al. (2012a), Yuan et al. (2012b)	1.31E-05	2	Roussos et al. (2012a)	Cruz et al. (2009), Roussos et al. (2012a)
CLDN11		9.04E-05	5	Tkachev et al. (2003), Katsel et al. (2005), Dracheva et al. (2006), Roussos et al. (2012a,b)
CNP	Peirce et al. (2006), Voineskos et al. (2008)	3.94E-03	19	Hakak et al. (2001), Katsel et al. (2005), Dracheva et al. (2006), McCullumsmith et al. (2007), Barley et al. (2009), Roussos et al. (2012b)	Prabakaran et al. (2004), Dracheva et al. (2006)
CNTNAP2	Friedman et al. (2008), Wang et al. (2010), Ji et al. (2013)	3.95E-04	10	Roussos et al. (2012a)
DISC1	Millar et al. (2000), Saetre et al. (2008), Song et al. (2008), Rastogi et al. (2009), Ayalew et al. (2012), Debono et al. (2012)	1.04E-03	13	Nakata et al. (2009)	Ratta-Apha et al. (2013)
ERBB3	Li et al. (2009)	9.70E-05	6	Tkachev et al. (2003), Katsel et al. (2005), Roussos et al. (2012b)
ERBB4	Norton et al. (2006), Silberberg et al. (2006), Agim et al. (2013)	2.80E-06	1	Silberberg et al. (2006), Law et al. (2007)	Chong et al. (2008)
MAG	Wan et al. (2005), Yang et al. (2005)	1.96E-03	16	Tkachev et al. (2003), Katsel et al. (2005), Dracheva et al. (2006), McCullumsmith et al. (2007), Barley et al. (2009), Roussos et al. (2012b)
MAL		8.23E-03	21	Hakak et al. (2001), Katsel et al. (2005)
MBP	Ayalew et al. (2012)	4.23E-04	11	Tkachev et al. (2003), Matthews et al. (2012)	Martins-de-Souza et al. (2009a,b)
MOBP	Ayalew et al. (2012)	6.65E-03	20	Tkachev et al. (2003)
MOG	Liu et al. (2005)	1.00E-02	23	Tkachev et al. (2003), Katsel et al. (2005), Barley et al. (2009), Roussos et al. (2012b)	Martins-de-Souza et al. (2009a)
NFASC		2.57E-04	8	Roussos et al. (2012a)
NRCAM	Ayalew et al. (2012)	1.14E-03	14	Roussos et al. (2012a)
NRG1	Stefansson et al. (2002), Ayalew et al. (2012), Weickert et al. (2012), Agim et al. (2013)	3.24E-05	3	Hashimoto et al. (2004), Law et al. (2006), Tan et al. (2007)	Chong et al. (2008)
OLIG2	Georgieva et al. (2006)	2.13E-03	17	Tkachev et al. (2003), Katsel et al. (2005)
PLP1	Qin et al. (2005)	NA	NA	Tkachev et al. (2003)
PMP22	Kirov et al. (2009)	1.38E-03	15	Katsel et al. (2005), Dracheva et al. (2006)
PTPRZ1	Buxbaum et al. (2008)	6.21E-05	4
QKI	Aberg et al. (2006b), Ayalew et al. (2012)	1.08E-04	7	Katsel et al. (2005), Aberg et al. (2006a), McCullumsmith et al. (2007)
RTN4R	Budel et al. (2008)	6.75E-04	12
SOX10	Maeno et al. (2007), Yuan et al. (2012a)	8.24E-03	22	Tkachev et al. (2003), Katsel et al. (2005), Dracheva et al. (2006)
CNTN2		2.57E-04	8	Roussos et al. (2012a),b
TF	Qu et al. (2008)	2.25E-03	18	Hakak et al. (2001), Katsel et al. (2005), McCullumsmith et al. (2007), Roussos et al. (2012b)	Prabakaran et al. (2004)

The largest PGC-SWE (Ripke et al., 2013) in the form of summary statistic p-values was obtained from public access website (https://pgc.unc.edu/). For each gene (±100 kb from 5′ and 3′ ends of gene), the strongest P value association is provided in the “PGC-SWE P” column. The “Rank” column indicates the ranking of the illustrated genes based on the strength of association with the schizophrenia GWAS data set.