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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Neurobiol Aging. 2013 Oct 23;35(3):669–679. doi: 10.1016/j.neurobiolaging.2013.09.031

Figure 8. Effect of pharmacological inhibition of ERK1/2 and ERK5 phosphorylation on the basal survival of human dopaminergic neuroblastoma SH-SY5Y cells.

Figure 8

SH-SY5Y cells were treated with U0126 (10 µM) and BIX02189 (10 µM) for 24 and 48 h. After 24 and 48 h, cell viability was determined by measurement of ATP levels using a Cell Titer-Glo Luminescent Cell Viability Assay. Data are expressed as mean ± SEM. ** p < 0.01 and *** p < 0.001 indicates a difference as compared to respective vehicle treatment by two-way ANOVA followed by the Bonferroni post hoc test.