Table 4.
Region | BA | x | y | z |
z-Value |
Activity pattern |
||
---|---|---|---|---|---|---|---|---|
n-Back version A | n-Back version B | n-Back version A | n-Back version B | |||||
MAIN EFFECT OF DIAGNOSTIC GROUP (CONTROL VS. SCHIZOPHRENIA) | ||||||||
L superior temporal gyrus | 22 | −64 | −32 | 13 | 2.92 | 3.66 | CON(−) < SCZ | CON(−) < SCZ |
L superior parietal lobule | 7 | −32 | −46 | 62 | 3.15 | 3.43 | CON < SCZ | CON < SCZ |
L cerebellum tonsil | − | −33 | −48 | −34 | 2.98 | 3.63 | CON < SCZ | CON < SCZ |
L cerebellum pyramis | − | −43 | −71 | −31 | 3.26 | 3.57 | CON < SCZ | CON < SCZ |
R supramarginal gyrus | 40 | 63 | −38 | 29 | 2.85 | 2.92 | CON(−) < SCZ | CON(−) < SCZ |
MAIN EFFECT OF PAST SUBSTANCE ABUSE (NO VS. YES) | ||||||||
L superior temporal gyrus | 22 | −63 | −17 | 2 | 2.73 | 2.96 | NSA(−) < SA | NSA(−) < SA |
L middle temporal gyrus | 21 | −65 | −37 | −12 | 3.04 | 3.71 | NSA(−) < SA | NSA(−) < SA |
L angular gyrus | 39 | −49 | −61 | 38 | 2.80 | 2.91 | NSA(−) < SA | NSA(−) < SA |
L posterior cingulate | 31 | −7 | −44 | 38 | 2.64 | 3.28 | NSA(−) > SA(−) | NSA(−) > SA(−) |
Activity patterns are activations, except when denoted with (−), indicating deactivation. Coordinates (x, y, z) reflect Talairach template space (57). BA, Brodmann area; L, left; R, right; CON, all control participants; SCZ, all schizophrenia patients; NSA, all participants without past substance abuse; SA, all participants with past substance abuse.