Table 4.
Subgroup | Observed events (N) | Expected events (N)* | HR; 95% CI | P-value | Absolute risk/100,000 PYAR | Excess risk/100,000 PYAR | Attributable percentage (%) |
---|---|---|---|---|---|---|---|
Sex | |||||||
Females | 310 | 201 | 1.54; 1.36–1.75 | <0.001 | 154 | 54 | 35 |
Males | 143 | 99 | 1.45; 1.21–1.75 | <0.001 | 118 | 37 | 31 |
Age | |||||||
0–19 yrs | 250 | 188 | 1.33; 1.16–1.53 | <0.001 | 172 | 43 | 25 |
20–39 yrs | 106 | 45 | 2.38; 1.90–2.98 | <0.001 | 179 | 104 | 58 |
40–59 yrs | 74 | 46 | 1.60; 1.24–2.08 | <0.001 | 100 | 37 | 38 |
≥60 | 23 | 22 | 1.03; 0.66–1.61 | 0.913 | 53 | 2 | 3 |
Calendar period | |||||||
-1989 | 67 | 34 | 1.98; 1.27–3.10 | 0.037 | 79 | 39 | 49 |
1990–1999 | 214 | 131 | 1.63; 1.40–1.89 | <0.001 | 134 | 52 | 39 |
2000–2008 | 172 | 118 | 1.46; 1.24–1.72 | <0.001 | 222 | 70 | 32 |
HR, Hazard ratio; CI, Confidence interval; PYAR, Person-years at risk.
Reference is general population comparator cohort.
Expected number of events in patients with celiac disease was derived from the observed number of events divided by the HR.