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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Gastroenterology. 2013 Jul 25;145(5):1121–1132. doi: 10.1053/j.gastro.2013.07.025

Figure 1. Immune cell infiltrate in human pancreatico-biliary diseases.

Figure 1

Immune cells infiltrates were measured in pancreatico-biliary diseases such as chronic pancreatitis (CP, n=4), mucinous cystic neoplasms (MCN, n=6), ampullary carcinoma (AC, n=9), pancreatic ductal adenocarcinoma (PDAC, n=93-98, shaded box), cholangiocarcinoma (CC, n=21) and normal tissues (N, n=11-14) using Ariol (Genetix) software as described in Supplementary Figures 1-4. Box (median with interquartile ranges (25th and 75th)) and whisker (5th and 95th centiles) plots (outliers are represented by individual dots) demonstrate that all diseases demonstrate significant, yet varied, density and profile for CD3+(A), CD4+(B), CD8+(C), CD20+(D), FoxP3+(E), and CD68+(F) immune cells infiltrate as compared by Kruskal-Wallis test (p-value < 0.0001 for all immune cells). Further statistical comparisons between columns were done by Dunn’s post test and indicated by *** p< 0.001; ** p= 0.001 to 0.01; * p= 0.01 to 0.05.