Table 3.
CMR Findings between LGE negative and LGE positive DMD patient compared to age and LVEF
| Parameters | # Patients | LGE negative | LGE positive | NPS with LGE | Odds ratio (95% CI) | P value |
|---|---|---|---|---|---|---|
| Age < 10 years |
83 |
69 (83%) |
14 (17%) |
4.4 ± 3.0 |
1.0 |
------- |
| Age 10–15 years |
149 |
98 (66%) |
52 (34%) |
4.8 ± 2.5 |
2.6 (1.3-5.0) |
< 0.006 |
| Age > 15 years |
82 |
34 (41%) |
48 (59%) |
5.9 ± 3.3 |
7.0 (3.4-14.3) |
< 0.0001 |
| LVEF ≥ 55% |
277 |
195 (70%) |
82 (30%) |
4.1 ± 2.4 |
1.0 |
------- |
| LVEF < 55% | 37 | 6 (16%) | 31 (84%) | 7.8 ± 3.4 | 12.3 (4.9-30.6) | < 0.0001 |
Abbreviations: # Number, CI Confidence Interval, CMR Cardiac Magnetic Resonance Imaging, DMD Duchenne Muscular Dystrophy, LGE Late Gadolinium Enhancement, LVEF Left Ventricular Ejection Fraction, NPS Number of Positive Segments.