Table 2.
Intrinsic connectivity networks in healthy controls.
| Anatomical region | L/R/Bi | Cluster | Z-score | p-value* | MNIa(x, y, z) |
|---|---|---|---|---|---|
| (A) ANTERIOR DEFAULT MODE NETWORK (aDMN) | |||||
| Medial prefrontal cortex | L | 1224 | >8.00 | <0.001 | 0, 50, −14 |
| Medial prefrontal cortex | R | ” | >8.00 | <0.001 | 6, 47, −5 |
| Posterior cingulate cortex | Bi | 47 | 6.14 | <0.001 | 0, −55, 19 |
| (B) INFERIOR POSTERIOR DEFAULT MODE NETWORK (ipDMN) | |||||
| Precuneus | L | 937 | >8.00 | <0.001 | −3, −52, 22 |
| Precuneus | R | ” | >8.00 | <0.001 | 3, −55, 19 |
| Angular gyrus | L | 40 | 7.33 | <0.001 | −45, −73, 37 |
| Angular gyrus | R | 17 | 6.06 | <0.001 | 48, −67, 31 |
| (C) SUPERIOR POSTERIOR DEFAULT MODE NETWORK (spDMN) | |||||
| Precuneus | R | 1444 | >8.00 | <0.001 | 6, −64, 43 |
| Precuneus | L | ” | >8.00 | <0.001 | 0, −79, 43 |
| Angular gyrus | L | ” | 6.20 | <0.001 | −36, −58, 40 |
| Angular gyrus | R | 56 | 6.15 | <0.001 | 36, −58, 37 |
| (D) SALIENCE NETWORK (SN) | |||||
| Anterior cingulate cortex | Bi | 948 | >8.00 | <0.001 | 0, 23, 28 |
| Anterior insula | L | 432 | >8.00 | <0.001 | −39, 14, −11 |
| Anterior insula | R | 400 | >8.00 | <0.001 | 51, 17, −11 |
| Middle frontal gyrus | R | 92 | 6.52 | <0.001 | 33, 53, 22 |
| (E) LEFT VENTRAL CENTRAL EXECUTIVE NETWORK (lvCEN) | |||||
| Angular gyrus | L | 653 | >8.00 | <0.001 | −45, −67, 31 |
| Inferior parietal gyrus | L | ” | 7.82 | <0.001 | −51, −52, 31 |
| Precuneus | L | 310 | 7.60 | <0.001 | −3, −61, 31 |
| Middle frontal gyrus | L | 345 | 6.73 | <0.001 | −45, 17, 49 |
| Inferior temporal gyrus | L | 24 | 6.27 | <0.001 | −63, −49, −17 |
| Superior medial gyrus | L | 33 | 5.55 | <0.001 | −9, 41, 40 |
| (F) RIGHT VENTRAL CENTRAL EXECUTIVE NETWORK (rvCEN) | |||||
| Superior frontal gyrus | R | 481 | 7.46 | <0.001 | 30, 26, 52 |
| Angular gyrus | R | 488 | 7.40 | <0.001 | 42, −73, 40 |
| Precuneus | R | 94 | 6.68 | <0.001 | 3, −61, 25 |
| Middle frontal gyrus | L | 25 | 6.49 | <0.001 | −24, 17, 58 |
| Temporal pole | L | 10 | 5.71 | <0.001 | −57, 11, −11 |
| (G) DORSAL CENTRAL EXECUTIVE NETWORK (dCEN) | |||||
| Supramarginal gyrus | L | 1099 | 7.79 | <0.001 | −60, −34, 37 |
| Inferior frontal gyrus | L | 182 | 7.22 | <0.001 | −45, 38, 7 |
| Inferior frontal gyrus | L | 109 | 7.04 | <0.001 | −48, 8, 22 |
| Inferior temporal gyrus | L | 161 | 6.75 | <0.001 | −57, −55, −11 |
| Superior frontal gyrus | L | 35 | 6.31 | <0.001 | −24, 5, 64 |
| Middle frontal gyrus | R | 9 | 5.84 | <0.001 | 51, 44, 10 |
*
One-sample-t-test, significant for p < 0.05, FWE-corrected for multiple comparisons, cluster-threshold >10 voxel.
a
MNI, Montreal Neurological institute; L, left hemisphere; R, right hemisphere; Bi, bilateral (see Figure 2).