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. Author manuscript; available in PMC: 2014 Jan 21.
Published in final edited form as: Neurobiol Dis. 2012 Jul 17;48(3):418–428. doi: 10.1016/j.nbd.2012.07.008

Fig. 6.

Fig. 6

Tregs isolated from mSOD1 mice during the rapidly progressing phase suppressed mSOD1 microglial (Mc) activation. Tregs from slowly progressing phase (100 day old) or from rapidly progressing phase (160 day old) mSOD1 mice were co-cultured with mSOD1 Mc for 2 days. Both 100 day Tregs and 160 day Tregs equally suppressed microglial NOX2 mRNA levels. Data shown as mean±SE of at least three independent experiments with duplicate or triplicate wells. **p<0.01 vs. WT Mc + WT Teffs; ##p<0.01 vs. Mc +Teffs in each group. WT = wild-type; Mc = microglia.