Table 1. Demographics of women in the total cohort comparing women with and without adverse maternal outcomes (N = 2,081).
Characteristic | Women with Adverse Outcomes (n = 401 women) | Women without Adverse Outcomes (n = 1,680 women) | p-Value* |
Demographics (within 48 h of eligibility) | |||
Maternal age at EDD (years)mean (±SD) | 27·9 (±5·9) | 28·5 (±6·2) | 0·17 |
Parity ≥1n (%) | 183 (45·6%) | 939 (55·9%) | <0·01 |
Gestational age at eligibility (wk)median [interquartile range] | 35·3 [30·7–38·1] | 37·1 [34·1–38·8] | <0·01 |
Multiple pregnancyn (%) | 17 (4·2%) | 57 (3·4%) | 0·41 |
Smoking in this pregnancyn (%) | 25 (6·2%) | 72 (4·3%) | 0·08 |
Pre-eclampsia description | |||
Pre-eclampsia n (%) | 320 (79·8%) | 1016 (60·5%) | <0·01 |
Other HDP n (%) | 81 (20·2%) | 664 (39·5%) | <0·01 |
Clinical measures (within 24 h of eligibility) | |||
Systolic BPmedian [interquartile range] | 170 [150–186] | 150 [140–170] | <0·01 |
Diastolic BPmedian [interquartile range] | 110 [100–120] | 100 [90–110] | <0·01 |
Worst dipstick proteinuriamedian [interquartile range] | 2+ [1+–3+] | 1+ [trace–3+] | <0·01 |
Number of symptomsmedian [interquartile range] | 1 [0–2] | 0 [0–1] | <0·01 |
Interventions at any time during admission | |||
Corticosteroid administrationn (%) | 180 (44·9%) | 525 (31·3%) | <0·01 |
Antihypertensive medications administeredn (%) | 386 (96·3%) | 1,560 (92·9%) | 0·13 |
MgSO4 administeredn (%) | 271 (67·6%) | 677 (40·3%) | <0·01 |
Pregnancy outcomes | |||
Admission-to-delivery interval (all cases) (d)median [interquartile range] | 1 [1]–[4] | 1 [1]–[5] | 0·02 |
GA on delivery (wk)median [interquartile range] | 35·7 [31·7–38·3] | 37·6 [35·3–39·1] | <0·01 |
Delivery at <34+0 wk GAn (%) | 160 (39.9%) | 290 (17.3%) | <0·01 |
Cesarean deliveryn (%) | 110 (27.4%) | 625 (37.2%) | <0·01 |
Birth weight (g)median [interquartile range] | 2,100 [1,303–2,800] | 2,700 [2,000–3,150] | <0·01 |
Birth weight <3rd percentile (N babies)n (%) | 64 (16·0%) | 284 (16·9%) | 0·66 |
Intrauterine fetal death(≥20+0 wk and/or ≥500 g)n (%) | 54 (13·5%) | 94 (5·6%) | <0·01 |
Neonatal death (before discharge)n (%) | 26 (6·5%) | 42 (2·5%) | <0·01 |
Results for continuous variables presented as mean (± standard deviation [SD]) when data normally distributed or median [interquartile range] for skewed data.
p-Values calculated using chi-squared test for categorical variables and Student's t-test or Mann-Whitney U for continuous variables.
EDD, estimated date of delivery; GA, gestational age.