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. Author manuscript; available in PMC: 2014 Dec 19.
Published in final edited form as: Cell. 2013 Dec 5;155(7):1451–1463. doi: 10.1016/j.cell.2013.11.024

Figure 5. B. fragilis Treatment Ameliorates Autism-Related Behavioral Abnormalities in MIA Offspring.

Figure 5

(A) Anxiety-like and locomotor behavior in the open field exploration assay. n=35–75/group

(B) Sensorimotor gating in the pre-pulse inhibition (PPI) assay. n=35–75/group

(C) Repetitive marble burying assay. n=16–45/group

(D) Ultrasonic vocalizations produced by adult male mice during social encounter. n=10/group

S=saline+vehicle, P=poly(I:C)+vehicle, P+BF=poly(I:C)+B. fragilis. Data were collected simultaneously for poly(I:C)+B. fragilisΔPSA and poly(I:C)+B. thetaiotaomicron treatment groups(See also Figures S3 and S4).