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. 2014 Jan 21;9(1):e85401. doi: 10.1371/journal.pone.0085401

Table 2. Recovery of lung-stage schistosomules from unimmunized and immunized mice 6 days after the challenge infection.

Vaccine formulation No. of mice tested No. of larvae/mouse ± SD P value
PBS (controls) 12 16.1±3.9 -
SmCB1 10 15.1±4.7 NS
FhCL1 8 15.1±3.1 NS
SmCB1+FhCL1 8 13.2±3.6 NS
SmCB1+SG3PDH/PRX MAP 6 7.5±3.4 0.0003*

For each experiment, lung-stage larvae were recovered from 2–3 mice per group, and counted on an individual mouse basis. Mean number ± SD around the mean of larvae retrieved from 2–6 repeat groups is shown. NS = not significant compared to PBS controls, as assessed using the Student 2-tailed t-test.

*

Immunization of mice with SG3PDH or PRX-MAP alone or emulsified with Freund's, alum, or Allison' adjuvant failed to elicit changes in number of lung-stage larvae recovered from immunized mice compared to adjuvant controls (data not shown).