Table 3. Characteristics of ART-suppressed group over time.
Pre-ART (N = 15) | First timepoint (N = 15) | Second timepoint (N = 15) | |
Age (Yrs) | 47 (25–60) | 50 (32–61) | 56 (34–64) |
Years infected | 6 (1–16) | 10 (6–20) | 13 (7–23) |
CD4 count/µL | 226 (36–573) | 482 (300–1079) ** | 462 (363 −1507) **, ! |
CD8 count/µL | 655 (476–1653)! | 1023 (484–1662) | 828 (353–2192) |
CD4∶CD8 ratio | 0.20 (0.07–0.44)! | 0.44 (0.21–1.52) ** | 0.60(0.18–2.30) **, ! |
Log viral load | 4.74 (3.88–>5.70) | 1.88 ** | 1.88 ** |
Yrs on suppressive ART | N/A | 3.7(1.0–6.9) | 5.5 (3.7–9.5) |
For three subjects, CD8+ T cell counts were not available at the pre-ART timepoint. Thus, CD8+ T cell count and CD4∶CD8 ratio at the pre-ART timepoint is based on 12 subjects.
= p<0.001 compared with pre-ART timepoint.
= p = 0.02 when compared with first on-ART timepoint.