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. 2014 Jan 21;9(1):e85566. doi: 10.1371/journal.pone.0085566

Table 3. Platelet parameters and clinical characteristics, n = 581.

Immature Immature Mean platelet
platelet fraction, % platelet count, 109/L volume, fL
No diabetes 2.5 (1.9;3.5) p = 0.15 5.7 (4.3;7.6) p = 0.07§ 10.7 (10.1;11.3) p = 0.06§
Type 2 diabetes 2.6 (2.0;3.7) 6.1 (4.5;8.4) 10.9 (10.3;11.5)
No prior MI 2.4 (1.8;3.7) p = 0.99 5.4 (4.5;7.8) p = 0.76 10.9 (10.2;11.5) p = 0.71
Prior MI 2.5 (1.9;3.5) 5.8 (4.4;7.8) 10.7 (10.2;11.3)
No current smoking 2.5 (1.9;3.4) p = 0.13§ 5.5 (4.2;8.7) p = 0.001* 10.8 (10.2;11.3) p = 0.30
Current smoking 2.6 (1.9;3.8) 6.7 (5.1;8.7) 10.8 (10.2;11.5)
Female 2.4 (1.7;3.4) p = 0.04* 5.7 (4.3;7.8) p = 0.35 10.8 (10.1;11.3) p = 0.51
Male 2.6 (1.9;3.6) 6.0 (4.6;7.9) 10.7 (10.2;11.4)
Age <65 years 2.5 (1.9;3.4) p = 0.67 5.9 (4.4;7.8) p = 0.30 10.7 (10.2;11.4) p = 0.82
Age ≥65 years 2.5 (1.9;3.6) 5.6 (4.2;7.7) 10.8 (10.2;11.3)
eGFR ≤60 mL/min 2.5 (1.9;3.4) p = 0.17 6.0 (4.5;8.0) p = 0.59 10.7 (10.2;11.3) p = 0.23
eGFR >60 mL/min 2.5 (1.9;3.6) 5.7 (4.3;7.8) 10.8 (10.2;11.4)
Platelet count Platelet distribution Platelet large
109/L width, fL cell ratio, %
No diabetes 227 (193;262) p = 0.70 13.0 (12.0;14.0) p = 0.02* 31 (26;36) p = 0.07§
Type 2 diabetes 219 (187;273) 13.5 (12.0;15.0) 32 (28;38)
No prior MI 223 (193;272) p = 0.60 13.9 (12.0;15.2) p = 0.43 33 (27;38) p = 0.69
Prior MI 226 (191;263) 13.0 (12.0;14.0) 31 (27;37)
No current smoking 222 (190;257) p = 0.003* 13.0 (12.0;14.0) p = 0.38 31 (27;36) p = 0.40
Current smoking 236 (199;289) 13.0 (12.0;15.0) 32(26;38)
Female 254 (221;298) p<0.0001* 13.0 (12.0;14.0) p = 0.45 32 (27;36) p = 0.50
Male 218 (186;255) 13.0 (12.0;14.0) 31 (27;37)
Age <65 years 232 (198;273) p = 0.001 13.0 (12.0;14.0) p = 0.28 31 (26;37) p = 0.92
Age ≥65 years 220 (185;256) 13.0 (12.0;14.1) 31 (27;36)
eGFR ≤60 mL/min 236 (207;279) p = 0.0003* 13.0 (12.0;14.0) p = 0.08 31 (26;36) p = 0.27
eGFR >60 mL/min 221 (185;256) 13.0 (12.0;14.4) 32 (27;37)

Data is presented as median (25th;75th percentile). Groups are compared using Mann-Whitney test.

p<0.05 in linear multivariate regression analyses adjusted for diabetes, prior MI, smoking, sex, age and eGFR.

p<0.10 in linear multivariate regression analyses adjusted for diabetes, prior MI, smoking, sex, age and eGFR.

MI: myocardial infarction, eGFR: estimated glomerular filtration rate.