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. 2014 Jan 21;9(1):e85722. doi: 10.1371/journal.pone.0085722

Table 4. Surfactant homeostasis is not corrected by additional NOS2 genetic ablation.

Surfactant Fraction
Small (µg) Large (µg) Total (µg)
WT (n = 7) 76±6 148±10 224±15
Sftpd−/− (n = 15) 604±39 * ξ 249±15 * ξ 854±49 * ξ
DiNOS (n = 7) 465±34 * ξ # 233±18 * ξ 698±42 * ξ
NOS2−/− (n = 8) 116±5 # 112±6 # 228±9 #

Phospholipid content of BAL as well as small and large aggregate fractions was determined by the method of Bartlett. Data shown are mean ± S.E.. Statistically significant differences between groups (p<0.05) are indicated as:

*

vs. WT,

ξ

vs. NOS2−/−,

#

vs. Sftpd−/− mice.