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. 2014 Jan 21;9(1):e85839. doi: 10.1371/journal.pone.0085839

Figure 3. Resolution of BALF inflammation and cytokine profile following allergen cessation.

Figure 3

Mice were challenged with OVA twice weekly for 12 weeks to establish features of chronic asthma; OVA challenge was then discontinued and replaced with PBS for 4 or 8 weeks (Protocol B). BALF inflammation was analysed after 12 (+ 0), 16 (+ 4) or 20 (+ 8) weeks of challenge. The results are presented as box and whisker plots showing mean and percentiles of n = 6–8 animals per group, *p≤0.05, **p≤0.01, ***p≤0.001.