Table 2. Serum concentrations of 25(OH)D3, PTH, total calcium, ionized calcium, urea and creatinine and clinical status of nine patients with psoriasis at baseline and after treatment with vitamin D (35,000 IU per day for 6 mo).
| Parameter (normal range) |
Baseline (mean ± SD) |
6 mo (mean ± SD) |
p value * |
|---|---|---|---|
|
25(OH)D3 (30–100 ng/mL) |
14.9 ± 7.4 | 106.3 ± 31.9 | < 0.0001 |
|
PTH (8–74 pg/mL) |
57.8 ± 16.7 | 28.9 ± 8.2 | 0.0039 |
|
Serum Calcium (8.4 – 11 mg/dL) |
9.7 ± 0.7 | 9.4 ± 0.7 | 0.1641 |
|
Ionized Calcium (1.10 – 1.40 mmol/L) |
1.4 ± 0.3 | 1.2 ± 0.2 | 0.1641 |
|
Urinary Calcium (100–300mg/24h) |
123.6 ± 60.0 | 226.8 ± 41.6 | 0.0039 |
|
Urea (< 50 mg/dL) |
35.8 ± 8.3 | 28.9 ± 9.8 | 0.1289 |
|
Creatinine (0.7 – 1.5 mg/dL) |
0.9 ± 0.2 | 0.8 ± 0.2 | 0.6406 |
*
Wilcoxon signed rank test