Table 3. Serum concentrations of 25(OH)D3, PTH, total calcium, ionized calcium, urea and creatinine and clinical status of 16 patients with vitiligo at baseline and after treatment with vitamin D (35,000 IU per day for 6 mo).
| Parameter (normal range) |
Baseline (mean ± SD) |
6 mo (mean ± SD) |
p value * |
|---|---|---|---|
|
25(OH)D3 (30–100 ng/mL) |
18.4 ± 8.9 | 132.5 ± 37.0 | 0.0005 |
|
PTH (8 – 74 pg/mL) |
55.3 ± 25.0 | 25.4 ± 10.7 | 0.0005 |
|
Serum Calcium (8.4 – 11.0 mg/dL) |
9.2 ± 0.3 | 9.2 ± 0.3 | 0.7615 |
|
Ionized Calcium (1.10 – 1.40 mmol/L) |
1.2 ± 0.2 | 1.2 ± 0.1 | 0.5417 |
|
Urinary Calcium (100–300mg/24h) |
158.3 ± 73.6 | 230.1 ± 81.4 | 0.0239 |
|
Urea (< 50 mg/dL) |
35.5 ± 7.2 | 33.9 ± 9.9 | 0.7148 |
|
Creatinine (0.7 – 1.5 mg/dL) |
0.9 ± 0.2 | 0.9 ± 0.2 | 0.5016 |
*
Wilcoxon signed rank test