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. 2014 Jan 21;9(1):e86105. doi: 10.1371/journal.pone.0086105

Table 3. Correlation between expression levels of MDL-1 and disease activity parameters as well as cytokine levels in 38 patients with rheumatoid arthritis.

Parameters MDL-1 expression on monocytes MDL-1 mRNA levels on PBMCs MDL-1 protein levels on SM
DAS28 0.392* 0.428** 0.613***
CRP, mg/dl 0.289* 0.395* 0.596**
Erosion score 0.569** 0.641*** 0.546**
JSN score 0.476** 0.484** 0.393*
IL-1β, pg/ml 0.437** 0.274* 0.389*
IL-6, pg/ml 0.468** 0.387* 0.410*
IL-17A, pg/ml 0.262* 0.280* 0.135
TNF-α, pg/ml 0.605*** 0.459** 0.321
DAP12 mRNA levels on PBMCs 0.656*** 0.702*** 0.447*
DAP12 protein levels on SM 0.119 0.207 0.462**

MDL-1: Myeloid DAP12-associated lectin-1; DAP12: DNAX adaptor protein 12; PBMCs: peripheral blood mononuclear cells; SM: synovial membranes; DAS28: disease activity score for 28-joints; CRP: C-reactive protein; JSN score: joint space narrowing score; IL-1β: interleukin-1β; IL-6: interleukin-6; IL-17A: interleukin-17A; TNF-α: tumor necrosis factor-α.

*

p<0.05, **p<0.005, ***p<0.001 were obtained by the nonparametric Spearman’s correlation test.