Table 2. Behavioral parameters recorded during the spatial memory test 24 hours after six spatial training trials in MR-Tg and MRCaMKCre mice and their control littermates.
| Females | Females | Males | ||||
| Behavioral parameters | MR-Tg | Control | MRCaMKCre | Control | MRCaMKCre | Control |
| General activity | ||||||
| Distance moved (cm) | 741±49 | 741±65 | 264±29*$# | 527±68 | 512±90 | 501±60 |
| Velocity (cm/s) | 6±1 | 6±1 | 2.5±0*$# | 4.5±1 | 4±1 | 4±1 |
| Total hole visits | 9±1 | 9±1 | 3±1*$# | 9±2 | 8±2 | 8±1 |
| Searching | ||||||
| Latency to exit quadrant (s) | 21±7 | 35±9 | 56±15 | 21±10 | 64±15 | 30±11 |
| Duration in exit quadrant (s) | 50±6∼ | 40±7 | 59±1∼$ | 69±7∼ | 29±8 | 47±8∼ |
| Average duration in other quadrants (s) | 21±2 | 23±2 | 14±4$ | 13±3 | 26±3 | 21±3 |
| Duration in holes zone (s) | 41±5 | 35±3 | 23±8*$# | 49±8 | 46±7 | 45±5 |
| % Perseveration | 16±3 | 13±3 | 5±3*$# | 17±4 | 12±4 | 11±3 |
Data represent mean ± SEM. Behavioral parameters that differ significantly; p<0.05: *vs same sex control littermates; #female MRCaMKCre vs MR-Tg; $male vs female MRCaMKCre; ∼duration in exit quadrant vs average duration in other quadrants.