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Effect of Aβ1-42 on tPA and PLG induction in mouse brain endothelial cells (bEnd.3) and pericytes. (A, B) RT-PCR (A) and western blot analysis (B) of tPA and PLG induction in mouse brain endothelial cells (bEnd.3) and pericytes. mRNA and protein samples were prepared 6 hr after exposure to 10 µM Aβ1-42 oligomers. Aβ1-42 did not affect tPA or PLG expression in endothelial (bEnd.3) or pericyte cultures.
