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. Author manuscript; available in PMC: 2014 Jun 15.
Published in final edited form as: Stat Med. 2012 Sep 21;32(13):2320–2334. doi: 10.1002/sim.5629

Table 2.

The estimates of the mean, standard error (SE), standard deviation (SD), and coverage probabilities (CP) of 95% credible intervals under various simulation scenarios.

regression model time to recurrence time to death

True β0 β1 β2 β3 p1 q1 p2 q2 γ11 γ12 α1 γ21 γ22 α2
pars 0.310 0.006 −1.800 0.700 0.800 0.850 0.900 0.700 −0.020 0.200 1.000 −0.004 0.700 3.000
(a) Simulate and estimate using piecewise constant function assuming conditional independence
Mean 0.337 0.008 −1.849 0.674 0.794 0.850 0.898 0.700 −0.021 0.205 0.992 −0.004 0.692 2.948
SD 0.136 0.011 0.281 0.309 0.035 0.030 0.023 0.036 0.005 0.107 0.134 0.005 0.120 0.243
SE 0.149 0.010 0.294 0.426 0.032 0.029 0.025 0.035 0.005 0.122 0.134 0.005 0.141 0.245
CP 0.990 0.910 0.960 0.990 0.950 0.970 0.960 0.950 0.950 0.990 0.950 0.950 0.990 0.950
(b) Simulate from Weibull and estimate using piecewise constant function assuming conditional independence
Mean 0.336 0.006 −1.808 0.693 0.797 0.856 0.896 0.702 −0.021 0.175 0.936 −0.004 0.680 2.746
SD 0.153 0.011 0.320 0.372 0.033 0.029 0.021 0.033 0.004 0.110 0.130 0.004 0.104 0.206
SE 0.147 0.010 0.293 0.426 0.032 0.028 0.025 0.035 0.005 0.116 0.125 0.005 0.129 0.222
CP 0.960 0.940 0.930 0.960 0.950 0.970 0.990 0.940 0.970 0.940 0.900 0.990 0.990 0.770
True β0 β1 β2 β3 p1 q1 p2 q2 γ11 γ12 α1 γ21 γ22 α2
pars 0.310 0.006 −1.800 0.700 0.800 0.850 0.830 0.638 −0.020 0.200 1.000 −0.004 0.700 3.000
(c) Simulate and estimate using piecewise constant function assuming conditional dependence
Mean 0.316 0.006 −1.813 0.668 0.803 0.857 0.836 0.642 −0.022 0.177 0.965 −0.005 0.699 2.984
SD 0.172 0.011 0.337 0.398 0.034 0.031 0.033 0.035 0.005 0.106 0.151 0.006 0.112 0.332
SE 0.165 0.011 0.308 0.449 0.034 0.033 0.031 0.037 0.005 0.124 0.141 0.006 0.148 0.278
CP 0.950 0.950 0.950 0.990 0.960 0.950 0.930 0.960 0.930 0.990 0.930 0.970 0.970 0.910
(d) Simulate from Weibull and estimate using piecewise constant function assuming conditional dependence
Mean 0.348 0.008 −1.838 0.721 0.791 0.858 0.825 0.639 −0.019 0.173 0.946 −0.003 0.668 2.665
SD 0.139 0.012 0.297 0.398 0.032 0.033 0.030 0.038 0.004 0.106 0.133 0.004 0.097 0.239
SE 0.164 0.011 0.307 0.454 0.034 0.032 0.032 0.037 0.005 0.117 0.134 0.005 0.135 0.252
CP 0.990 0.920 0.970 0.970 0.960 0.960 0.960 0.920 0.960 0.950 0.910 0.970 0.990 0.740