Table 2. [18F]-FMZ binding parameters in the left hippocampus as derived from the partial saturation model using a multi-injection protocol.
Rat | Bmax (pmol/ml) | K1 (pmol/ml) | k2 (pmol/ml) | kon/Vr (pmol/ml) | koff (pmol/ml) | KdVr (pmol/ml) | 1/KdVr (pmol/ml) | DV1 (pmol/ml) | BP |
A | 27.26 | 0.23 | 0.77 | 1.24 | 4 | 3.23 | 0.31 | 0.29 | 8.44 |
B | 29.29 | 0.30 | 0.71 | 1.67 | 4 | 2.39 | 0.42 | 0.42 | 12.23 |
C | 38.92 | 0.39 | 0.70 | 1.14 | 4 | 3.49 | 0.29 | 0.56 | 11.13 |
D | 27.91 | 0.12 | 0.33 | 0.76 | 4 | 5.26 | 0.19 | 0.37 | 5.31 |
Mean | 30.85 | 0.26 | 0.63 | 1.20 | 4 | 3.60 | 0.30 | 0.41 | 9.28 |