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. 2014 Jan 21;9(1):e86573. doi: 10.1371/journal.pone.0086573

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© 2014 Zhao et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Neutralization titers of MixBiEDIII immune sera at two weeks after the last immunization were measured by PRNT₅₀. The neutralizing antibodies against four DENV serotypes were significantly induced by MixBiEDIII compared with control group. Dotted line represents limits of detection.