Figure 4. PDA-001 cell treatment promotes endothelial cell proliferation, vascular density and perimeter and increases synaptophysin expression in older rats after MCAo.

Panels A–C show that PDA-001 treatment significantly increased endothelial cell proliferation (A), vascular density (B) and vascular perimeter (C) in the IBZ in older rats. Panel D shows that PDA-001 treatment significantly increased synaptophysin expression in IBZ in older rats. Error bars represent standard error of the mean (mean±SE).