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. 2014 Jan 21;9(1):e86649. doi: 10.1371/journal.pone.0086649

Table 1. CAYP1A1 3801T >C genotype distribution and allele frequencies in cases and controls.

Study Year Country Ethnicity Control source Genotyping method Cases/controls Genotype data (cases) Genotype data (controls) MAF HWE (P)a Quality score
T C TT TC CC T C TT TC CC
Lu et al [27] 2008 China Asian HB PCR-RFLP 192/226 234 150 69 96 27 294 158 95 104 27 0.35 0.86 6
Vani et al [28] 2009 India Caucasian HB PCR-RFLP 206/230 296 116 108 80 18 372 88 146 80 4 0.19 0.06 8
Chen et al [29] 2010 China Asian HB PCR-RFLP 105/140 117 93 35 47 23 221 59 88 45 7 0.21 0.69 5
Peng et al [30] 2012 China Asian HB PCR-RFLP 204/202 237 171 72 93 39 250 154 78 94 30 0.38 0.85 5
Salehi et al [31] 2012 Iran Caucasian HB PCR-RFLP 150/200 188 112 58 72 20 261 139 85 91 24 0.35 0.96 6
Yarosh et al [32] 2013 Russia Caucasian HB PCR-RFLP 203/227 365 41 165 35 3 400 54 176 48 3 0.12 0.89 8

HB hospital based, PCR-RFLP polymerase chain reaction-restriction fragment length polymorphism, MAF minor allele frequency, HWE Hardy–Weinberg equilibrium,

a

P value for HWE in control group.