Table 3.
Clinical and laboratory variables according to CTRP-3 level tertiles
| First tertile | Second tertile | Third tertile | P | |
|---|---|---|---|---|
| CTRP-3 (ng/ml) |
267.7 (239.6, 291.5)a |
367.8 (347.0, 401.0)b |
553.8 (477.9, 634.9)c |
<0.001 |
| Age (years) |
59 (54, 67)a |
58 (55, 68)a |
61 (58, 69)b |
0.019 |
| Weight (kg) |
67.8 ± 9.6a |
66.3 ± 11.7a |
63.2 ± 10.7b |
0.004 |
| BMI (kg/m2) |
24.4 ± 2.6 |
24.6 ± 3.0 |
24.0 ± 3.0 |
0.350 |
| Waist circumference (cm) |
85.9 ± 7.7a |
85.2 ± 8.2a |
82.5 ± 9.1b |
0.011 |
| SBP (mmHg) |
119 (112, 128) |
123 (109.5, 134) |
120.5 (109.5, 132) |
0.570 |
| DBP (mmHg) |
75.4 ± 12.0 |
78.2 ± 12.2 |
75.4 ± 11.1 |
0.110 |
| Total cholesterol (mmol/l) |
4.7 ± 1.1 |
4.6 ± 1.0 |
4.7 ± 1.0 |
0.616 |
| LDL-cholesterol (mmol/l) |
3.2 ± 0.9 |
2.9 ± 0.9 |
3.1 ± 0.8 |
0.111 |
| Triglyceride (mmol/l) |
1.3 (0.9, 2.0) |
1.3 (0.9, 2.0) |
1.2 (0.9, 1.6) |
0.132 |
| HDL-cholesterol (mmol/l) |
1.2 (1.0, 1.5)a |
1.2 (1.1, 1.4)a |
1.3 (1.2, 1.6)b |
0.001 |
| Glucose (mmol/l) |
5.7 (5.3, 6.4)a,b |
5.8 (5.3, 6.5)a |
5.5 (5.1, 6.0)b |
0.029 |
| Creatinine (mg/dl) |
0.8 (0.7, 0.9) |
0.8 (0.6, 0.9) |
0.8 (0.7, 0.9) |
0.080 |
| eGFR (mL/min/1.73 m2) |
96.2 (84.1, 110.1) |
97.9 (84.8, 110.7) |
91.5 (82.0, 107.4) |
0.127 |
| hsCRP (mg/dl) |
0.6 (0.2, 1.4) |
0.7 (0.1, 1.4) |
0.5 (0.1, 0.9) |
0.157 |
| Progranulin (ng/ml) |
165.0 (135.9, 191.1) |
169.4 (144.0, 213.2) |
171.4 (148.8, 210.6) |
0.116 |
| Adiponectin (μg/ml) | 6.4 (4.8, 8.5)a | 6.5 (5.2, 8.6)a | 8.6 (6.5, 11.7)b | <0.001 |
Data are expressed as mean ± standard deviation or median (inter-quartile range).
SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL, low-density lipoprotein; HDL, high-density lipoprotein; eGFR, estimated glomerular filtration rate; hsCRP, high-sensitivity C-reactive protein; CTRP-3, C1q/TNF-related Protein-3.