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. 2014 Jan 15;15:18. doi: 10.1186/1471-2105-15-18

Figure 2.

Figure 2

Analyzing different molecular aspects of genes and proteins. a) Identification of disease genes – The user is interested in the disease Ectodermal dysplasia. From the returned list she focuses on autosomal recessive hypohidrotic ectodermal with three associated genes (red enclosed region). b) Interacting proteins – The graph shows the interaction network containing all genes which directly interact with the three genes in the snapshot. This interaction network comprises 58 genes. c) Identification of drug targets – 7 of the interacting genes are targets of known drugs. d) Integration into metabolic networks – One of the identified genes is involved in Glycolysis / Gluconeogenesis. Enzymes present in the snapshot are highlighted turquoise. Other enzymes present in the human genome are highlighted grey. Enzymes absent from the genome are not highlighted.