Table 4. Linear regression models for a 1-kg increase in birth weight.
| Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | Model 6 | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Outcome |
N |
Coeff |
95% CI |
Pa |
Coeff |
95% CI |
Pa |
Coeff |
95% CI |
Pa |
Coeff |
95% CI |
Pa |
Coeff |
95% CI |
Pa |
Coeff |
95% CI |
Pa |
| Cystatin C–based eGFR (ml/min per 1.73 m2) | 1447 | 2.25 | 0.80 to 3.71 | 0.002 | 2.19 | 0.73 to 3.64 | 0.003 | 2.05 | 0.60 to 3.50 | 0.005 | 2.07 | 0.62 to 3.51 | 0.005 | 2.41 | 0.96 to 3.86 | 0.001 | 2.24 | 0.80 to 3.69 | 0.002 |
| Creatinine and cystatin C–based eGFR (ml/min per 1.73 m2) | 1316 | 2.13 | 0.69 to 3.58 | 0.004 | 2.09 | 0.65 to 3.54 | 0.004 | 1.97 | 0.52 to 3.42 | 0.007 | 2.01 | 0.57 to 3.46 | 0.006 | 2.31 | 0.86 to 3.76 | 0.002 | 2.15 | 0.71 to 3.60 | 0.003 |
| Log-urine albumin–creatinine ratio (mg/mmol) | 1465 | −0.019 | −0.094 to 0.056 | 0.62 | −0.013 | −0.089 to 0.062 | 0.73 | −0.003 | −0.078 to 0.072 | 0.94 | 0.009 | −0.066 to 0.083 | 0.82 | −0.020 | −0.096 to 0.055 | 0.59 | 0.010 | −0.065 to 0.085 | 0.79 |
Abbreviations: CI, confidence interval; Coeff, coefficient; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin.
Restricted to study members nonmissing for childhood and adulthood socioeconomic status, self-reported diabetes by the age of 60–64 years, on diabetes treatment at the age of 60–64 years, HbA1c at the age of 60–64 years, midlife systolic blood pressure trajectory, on hypertension treatment at the age of 60–64 years, systolic blood pressure at the age of 60–64 years, and overweight at the age of 36 years.
Model 1: minimally adjusted for sex and age at renal function measurement; model 2: model 1+childhood and adulthood socioeconomic position; model 3: model 2+self-reported diabetes by the age of 60–64 years+on diabetes treatment at the age of 60–64 years+HbA1c at the age of 60–64 years; model 4: model 2+midlife systolic blood pressure trajectory+on hypertension treatment at the age of 60–64 years+systolic blood pressure at the age of 60–64 years+diastolic blood pressure at the age of 60–64 years; model 5: model 2+overweight at the age of 36 years; model 6: model 2+self-reported diabetes by the age of 60–64 years+on diabetes treatment at the age of 60–64 years+HbA1c at the age of 60–64 years+midlife systolic blood pressure trajectory+on hypertension treatment at the age of 60–64 years+systolic blood pressure at the age of 60–64 years+diastolic blood pressure at age 60–64 years+overweight at age 36 years.
Wald test.