Table 2.
Subgroup analyses for odds ratio of in-hospital or 30 day mortality due to acute myocardial infarction during off-hours compared with regular hours
| Subgroup | No of cohorts | Odds ratio (95% CI) | I2 (%) | P value for interaction |
|---|---|---|---|---|
| Diagnosis*: | ||||
| STEMI | 25 | 1.12 (1.03 to 1.22) | 42 | <0.01 |
| Non-STEMI | 2 | 0.96 (0.91 to 1.02) | 0 | |
| Type of off-hours: | ||||
| Weekend and night | 22 | 1.09 (1.00 to 1.18) | 57 | 0.25 |
| Weekend | 16 | 1.06 (1.03 to 1.09) | 85 | |
| Night | 4 | 1.88 (0.93 to 3.80) | 70 | |
| Measured time of presentation: | ||||
| Arrival | 6 | 1.02 (0.93 to 1.10) | 56 | 0.27 |
| Admission | 24 | 1.07 (1.04 to 1.10) | 82 | |
| Start of PCI | 12 | 1.20 (0.97 to 1.47) | 47 | |
| Data source: | ||||
| Clinical registry | 27 | 1.11 (1.02 to 1.21) | 58 | 0.29 |
| Administrative data | 15 | 1.06 (1.03 to 1.09) | 86 | |
| Region†: | ||||
| North America | 15 | 1.03 (1.01 to 1.04) | 49 | <0.01 |
| Europe | 18 | 1.08 (1.02 to 1.15) | 53 | |
| Others | 8 | 1.25 (1.15 to 1.36) | 15 | |
| Outcome adjustment: | ||||
| Adjusted | 30 | 1.07 (1.04 to 1.10) | 75 | 0.28 |
| Unadjusted | 12 | 1.19 (0.98 to 1.44) | 48 |
PCI=percutaneous coronary intervention; STEMI=ST elevation myocardial infarction.
*One study reported results by two different diagnosis groups (STEMI and non-STEMI).
†One study reported outcome from 11 countries across continents.