Table 3.
Overall and subgroup analyses for mean difference of door to balloon times for STEMI patients during off-hours compared with regular hours
| Subgroup | No of cohorts | Mean difference (95% CI) in minutes | I2 (%) | P value for interaction |
|---|---|---|---|---|
| All studies | 29 | 14.8 (10.7 to 19.0) | 99 | |
| Type of off-hours*: | ||||
| Weekend and night | 21 | 15.8 (10.5 to 21.0) | 99 | 0.37 |
| Weekend | 3 | 17.8 (9.0 to 26.6) | 70 | |
| Night | 7 | 10.6 (3.7 to 17.4) | 93 | |
| Measured time of presentation: | ||||
| Arrival | 12 | 20.0 (16.1 to 23.8) | 98 | <0.01 |
| Admission | 8 | 12.3 (4.5 to 20.1) | 83 | |
| Start of PCI | 9 | 7.1 (3.2 to 11.0) | 92 | |
| Region†: | ||||
| North America | 12 | 20.8 (16.5 to 25.0) | 83 | <0.01 |
| Europe | 11 | 7.2 (3.6 to 10.9) | 97 | |
| Others | 5 | 21.3 (4.4 to 38.2) | 89 |
PCI=percutaneous coronary intervention; STEMI=ST elevation myocardial infarction.
*Two studies reported results for weekend presentations as subgroup analysis.49 50
†One study reported outcome from 11 countries across continents.39